Enhanced Healthcare Toxicity Assessment

Enhanced Toxicity Score (ETS) = Σ[Wi × Fi × Ii × Ti × Ci] + Σ[Iij × Fi × Fj] + Σ[Nk × Rk] + ε

Where:
Wi = Dynamic weights from ensemble ML models
Fi = Individual factor scores (0-10 scale)
Ii = Impact multipliers based on severity curves
Ti = Temporal decay functions
Ci = Contextual adjustment factors
Iij = Interaction terms between factors i and j
Nk = Non-linear transformation functions
Rk = Resilience and recovery factors
ε = Stochastic error term

Dynamic Weight Calculation:
Wi(t) = αi × RFi + βi × GBi + γi × NNi + δi × Bi

Where:
RFi = Random Forest importance score
GBi = Gradient Boosting feature importance
NNi = Neural Network attention weights
Bi = Bayesian posterior probability
αi, βi, γi, δi = Meta-learning coefficients

Interaction Terms:
Iij = ρij × √(Fi × Fj) × log(1 + |Fi - Fj|)

Temporal Decay:
Ti = e^(-λi × Δt) × (1 + μi × frequency)

Severity Curves:
Ii = 1 + (Fi/10)^κi × σi